Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome
About
Immune-mediated, non-communicable diseases, such as autoimmune diseases, allergic diseases and asthma, are chronic disorders in which the immune system plays a pivotal role. The World Health Organisation (WHO) has highlighted the seriousness of autoimmunity and its association with exposure to the environment.
EXIMIOUS aims to deliver a new way of assessing the human exposome, i.e. the exposures to environmental factors that one experiences throughout life, and shed light on its association to immune-mediated diseases.
Partners
EXIMIOUS is part of the European Human Exposome Network and brings together 15 partner organisations from 7 European countries.
FAQ
Don’t know what the exposome is?
Want to know more about exposure-related immune diseases?
Curious to know more about what to expect from this project?
Latest news
New publication: Dynamic biodistribution of inhaled silica particles to extrapulmonary sites: Early and late translocation mechanisms with implication for particle biomonitoring
In our latest study we quantified for the first time the systemic redistribution of crystalline silica particles deposited in the lungs of mice, using an innovative approach based on ICP-MS spectroscopy. Specifically, we demonstrated that 30% of inhaled crystalline particles translocate into extrapulmonary sites including immune organs – such as the liver (13%), spleen (2%),
OCCUPATIONAL EXPOSOME Week 2025 Wrap-Up: Advancing Workplace Exposure Science Across Europe
The Occupational Exposome Week has concluded with resounding success, bringing together over 500 participants from across Europe and beyond to explore the latest developments in occupational exposure science. Held from 20–26 March 2025, this five-part webinar series was jointly organised by the EXIMIOUS and EPHOR projects, both funded under the European Commission’s Horizon 2020 research
Register for the “OCCUPATIONAL EXPOSOME WEEK” – 20-26 March 2025
Funded by the European Commission’s Horizon 2020 research and innovation programme, EXIMIOUS and EPHOR focus on delivering a new way of assessing the human exposome, specifically the occupational exposome. Both projects are part of the European Human Exposome Network (EHEN). The symposia are open to all audiences and will explore key topics related to occupational
Project facts
EXIMIOUS is a 5 year Research and Innovation Action funded by the European Union’s Horizon 2020 programme.
- Concept: introduce a new approach to mapping exposure-induced immune effects by combining exposomics and immunomics in a unique toolbox.
- Budget: 10.8 million Euro
- Duration: 01.01.2020 - 31.12.2024
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 874707.
